SIMONCINI MORE

A1: I communicated for many years with Dr. Simoncini and even sent patients to him.  I did the intravenous sodium bicarbonate protocols as he described but this did not give me dramatic results in my cancer patients.

Victor A Marcial-Vega,MD

Board Certified Oncologist

122 Eleanor Roosevelt, Interior,

San Juan, Puerto Rico, 00918

Tel 787-767-2587

www.marcialvegamd.com

marcialvegamd@aol.com

9260 SW Sunset Drive, Suite 219,

Miami, Florida, 33176

305-275-1098

A2:    I treated 3 patients—poor results—one became quite edematous from all the sodium.

   Some cancer centers thing it is not a good therapy—rather alkalize orally and use other methods such as Mega Vitamin C with or without DMSO, some swear by PolyMVA( I have mixed results) , salicinium ( I was not that impressed—caused a lot of discomfort in my stage 4 patients—often bone pain ) Alpha lipoid acid and Glutathione pushes

   Look into two other “helpers ”  : Very high doses of Vitamin D  ( monitor serum calcium ) and fermented soy ( especially in brain tumors ). Cannot do any harm giving apricot kernels (15+ every day ). Get a ph meter—test your patients 2 times /week—remember mega vitamin C since ascorbic acid—have to work hard to get pH over 7

  DR George Allibone MD

A3: In my Expert Opinion, Cancer is clearly a disease of the internal and external cell membranes.    Cancer is caused by trans fats and bad oils.   Cancer is cured with good oils.   Cancer is caused by sick mitochondria, heal the mitochondrial membranes and repair the Krebs Cycle restoring Oxygen utilization and the cancer cell will die on their own, apoptosis.      It is just as simple as that.   That’s  one way to cure cancer without killing your patient.           The oxidation action of the iv Vitamin C that we are all familiar with is one important aspect of inducing apoptosis.   Another important characteristic of Vitamin C is that acts as an electron exchanger helping bypass stuck electron jams in the mitochondrial electron chain transport systems. Normal cellular energy = no cancer.

Many patients state that they benefit from baking soda and molasses to alkalize something or other.      I find this somewhat amazing since backing soda is an acid generally used as an acid buffer.   Furthermore the excess bicarb is blown off as CO2 providing very little buffering capacity internally.  Regardless of how much acid you add to a mixture it will never go alkaline.

My money is on the molasses which is the vegetable juice concentrate from the sugar cane plant minus most of the sugars.    Molasses is loaded with vitamins and minerals.    The juice from the leaves of edible plants is a standard modality in cancer therapy as are many trace minerals and various vitamins so why not molasses the reduced sugar juice of sugar cane?

Furthermore, As you know the the pH is determined by the ash not the taste of the food.    Molasses high in minerals minus the sugar has an alkalizing action.

Baking Soda may be beneficial also for some reason.  I just don’t know what that might be.

Dr. Myron Berney, ND LAc

A4: FACT members:  I believe this is a bad idea.  On so many levels.

First, sodium is a shallow alkalinizer.  Most of its alkaline effects are delivered to the blood stream, which is tightly pH regulated.  It has some alkalinizing effect at the tissue level, but has minimal effects at the cellular level (potassium is better than sodium), the organelle level (rubidium is better), and at the subnuclear

(DNA/histone) level (cesium is better).  I suggest that cancer involves cellular and subcellular pH disturbances as primary effects.  Tissue and blood pH effects are a consequence of deeper pathologies.

Second, there are often seemingly paradoxical pH imbalances between different aqueous compartments of the body.  Even if you knew that the pH of the blood was slightly acid, and the tissue pH strongly acid, the likely metabolic cause would be lactic acidosis from anaerobic dominant energy metabolism at the cellular and subcellular levels.  Sodium carbonate might possibly mitigate this, but it certainly would not be an aerobic influence.  In other words, sodium bicarbonate would be a symptomatic treatment only.  Aerobic influences would be causally directed.  I’ve listed these in earlier posts, so I won’t waste your time here.

Third, since lactic acid can also be a direct consequence of a low metabolic rate, it suggests a primary pathology at the subcellular level.  Mitochondrial dysfunction, insulin resistance, metabolic entrainment, suppression of beta-oxidation, inadequate NADH coupling from the Krebs cycle to the electron transport chain, heavy metals, environmental toxins (pesticides) or dietary toxins (phytotoxins, mycotoxins, allergens).  There might also be higher-level pathologies involving the support systems to these underlying levels, like impairment of lung function (COPD, lung scar tissue, smoking tars, infections), cardiovascular disease (circulatory impairment, coagulopathy, plaque), and neuroendocrine dysfunctions (low thyroid activity, low progesterone, low testosterone, low cortisol, high estradiol, high estrone, high cortisol), but the only mechanism I know by which bicarbonate could decisively effect these higher mechanisms is in improving hemoglobin function in red blood cells.  The O2 binding and release functions of hemoglobin are highly pH sensitive, and sodium bicarbonate could benefit this.  But then again, if the blood is alkaline stressed or overly alkaline buffered, it might make it much worse.

Fourth, the observed benefits of sodium carbonate in clinical practice may be mostly due to the carbonate.  CO2 deficiency is expected in hypometabolic and anaerobic-dominant individuals.  And if carbonate is the target, carbonate salts other than sodium are likely to be more effective.  But even so, raising natural carbonate production is a much more sensible approach. Sustainable, too.

I believe that the benefits of an alkaline diet and alkaline supplementation are in their ability to “balance” (and facilitate) increased acid from aerobic energy production at the subcellular level.  Aerobic systems generate acid (carbonic acid) which is easy to pH balance and readily diffuses through metabolic compartments of the body to the lungs.  When the aerobic systems flounder or fail, the anaerobic systems generate lactic acid, which can accumulate in the cells and definitely accumulates in the tissues, which is not easily pH balanced or diffused.  If this is true, then alkaline diets need to be accompanied by concurrent aerobic therapies, and there needs to be ongoing clinical assessment of the “balance” between the dietary alkaline ash and the increased aerobic metabolic activity.

A word of caution re IV potassium carbonate (or chloride).  Serum potassium data is misleading re potassium status in hypometabolic individuals.  Medical doctors are taught that serum potassium and cellular potassium always track together.  This is not true in hypometabolic or hypermetabolic individuals; only in normo-metabolic individuals.  In cancer, hypometabolism is the norm.  In hypometabolism, potassium tends to be over-utilized at the cellular level, which decreases serum reading and increases cellular readings.  If you use IV therapies containing potassium, do not use only serum potassium data to guide sufficiency of treatment.  By the time serum potassium levels reach 4.5 mEq/l, cellular potassium levels can be high enough to cause heart failure.  If your client cannot afford expensive cellular potassium testing, use total-blood potassium testing to monitor potassium sufficiency.  This can be cheaply and conveniently done by diluting one cc of whole blood into 9 cc of distilled or deionized water and running the hemolyzed sample through standard serum testing equipment.  Then multiply the result by ten to restore the units.  38 mEq/l is a normative level for total-blood potassium (i.e., 3.8 mEq/l from the serum test machine). —Steve  650-321-2374

A5: Physiologically speaking, the pH of human blood and organs is very precisely controlled by carbonic acid and sodium bicarbonate buffer, pH 7.4 +/- 0.2. Thankfully, no diet or water pH can change it.

At a Cancer Control Siciety meeting in Los Angeles about three years ago Dr. Simochini stated that he never microbiologically tested the white substance of tumors for Candida albicans that he professed to be the infectious constituent of tumors. One breast cancer patient treated by the Doctor presented with new tumors at the injection sites of baking soda. Her Cancer Profile markers also increased considerably and JP’s condition deteriorated to total demise. Naturally, one case does not warrant final conclusions.

The PHI enzyme, The Human Autocrine Motility Factor neurokine is most likely responsible for early metastasis and the circulating tumor cell. The unaerobic metabolism regulating enzyme at abnormal concentrations will dock on genetically created sites on the cell’s surface, causes vibration, dislodgement of the cell, cytokinesis. The abnormal apperance of phosphohexsoseisomerase, years before cancer tumor diagnosis can be made, may well be an indication of metastatic phenomenon, years prior to tumor visualization. For more information, see www.AmericanMetabolicLaboratories.net

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